Blastoma

IMAGE: A) Arsenic Trioxide (ATO) reduces the clonogenic capacity of medulloblastoma (MB) cell lines of the SHH subgroup (DAOY: TP53 c.725G>T; UW402: TP53 c.464C>A and ONS-76: TP53 wild type). B) Clonogenic... view more  Credit: Paulo Henrique dos Santos Klinger By André Julião | Agência FAPESP – Researchers affiliated with the University…

AbstractCell division and organismal development are exquisitely orchestrated and regulated processes. The dysregulation of the molecular mechanisms underlying these processes may cause cancer, a consequence of cell-intrinsic and/or cell-extrinsic events. Cellular DNA can be damaged by spontaneous hydrolysis, reactive oxygen species, aberrant cellular metabolism or other perturbations that cause DNA…

Loading metrics Open Access Peer-reviewed Research Article Melissa F. Adasme , Daniele Parisi , Kristien Van Belle, Sebastian Salentin, V. Joachim Haupt, Gary S. Jennings, Jörg-Christian Heinrich, Jean Herman, Ben Sprangers, Thierry Louat, Yves Moreau, Michael Schroeder Melissa F. Adasme,  Daniele Parisi,  Kristien Van Belle,  Sebastian Salentin,  V. Joachim Haupt, …

Loading metrics Open Access Peer-reviewed Research Article Tomoya Kitakaze,  Atsushi Makiyama,  Yoko Yamashita,  Hitoshi Ashida x Published: April 9, 2020 https://doi.org/10.1371/journal.pone.0231403 AbstractA flavone luteolin has various health-promoting activities. Several studies reported that high dose of luteolin activates the Nrf2/ARE pathway in the liver. However, the effect of the low dose…

Kim Strong York Daily RecordPublished 2:28 PM EDT Mar 8, 2020YORK, Pa. – Eve and Ella Oakley’s wish has come  true. The twins are on vacation in Florida.They’re taking a break from the hospitals and tests and therapies in their battle with cancer, a war they’ve waged since they were born two…

YORK, Pa. – Eve and Ella Oakley’s wish has come  true. The twins are on vacation in Florida.They’re taking a break from the hospitals and tests and therapies in their battle with cancer, a war they’ve waged since they were born two years ago.And it isn’t the only battle they’ve endured.“Literally, the…

1.Korshunov, A. et al. Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity. Acta Neuropathol. 128, 279289 (2014).

1.Korshunov, A. et al. Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity. Acta Neuropathol. 128, 279289 (2014).

It was back in November 2015 when Lynsay Hughes and her husband Andrew, a project engineer, both 38, first noticed their two-year-old Evie was out of sorts. Wed begun potty training and it was going really well, but Evie suddenly started refusing to go to t…

A three-year-old boy, diagnosed with a rare type of lung cancer (pulmonary blastoma) that gave him just days to live, has beaten the odds to come back to life after a successful surgery at a city hospital. Little Mohammed Haidan has literally come back from …