Blastoma

KUALA LUMPUR: Malaysia reported 2,464 Covid-19 infections today, the second time since Feb 9 that the daily case figures had dipped below the 3,000-mark. Health director-general Tan Sri Dr Noor Hisham Abdullah said the country’s Covid-19 infection tally now stands at 264,269, of which 49,490 are active cases. There was…

IMAGE: Dr. Cheryl Arrowsmith is one of three senior authors publishing research on a different strategy to stop brain cancer cells from growing. view more  Credit: The Princess Margaret Cancer Foundation (Friday, February 12, 2021 - Toronto) -- Inhibiting a key enzyme that controls a large network of proteins important in…

The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. The researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH) and the Princess Máxima Center for Pediatric Oncology, discovered that all neuroblastomas arise from a single…

The daughter of a mum dying from terminal cancer has opened up about how the coronavirus pandemic has made their their grief and distress even worse. Wendy Kowalski, from Llansamlet, was diagnosed with grade four glioblastoma in February 2017. It is the most aggressive kind of cancer that begins within…

New research suggests that a drug used to slow down an upset digestive tract may actually be useful in the treatment of cancer. The medication, called loperamide, is often used to treat diarrhea, but it can also induce the destruction of certain tumor cells.  Additional research is needed, but the…

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue. GBM cells insinuate themselves in the interstitial space of the neural tissue and migrate along blood vessels to more distant locations…

The US Food and Drug Administration (FDA) has granted accelerated approval for a new drug for certain patients with neuroblastoma based on response rate results in small open-label trials. The drug is naxitamab (Danyelza, Y-mAbs Therapeutics), a humanized monoclonal antibody that targets GD2 3F8, a disialoganglioside highly expressed on neuroblastomas. The product…

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation.…

IMAGE: A test run of the personalized drug screen was completed using a brain tumor from an 8-year-old boy newly diagnosed with metastatic medulloblastoma. An information package about his tumor, including... view more  Credit: Rady Children's Hospital-San Diego Scientists at Sanford Burnham Prebys Medical Discovery Institute, University of California San Diego…

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