Blastoma

McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy. Due to its resistance to therapy, glioblastoma is the most common and aggressive cancerous brain tumour in adults. It…

Josie Rock was taking pictures of her 3-month-old son Asher when the lighting in the room suddenly dimmed, initiating the flash on her iPhone. Asher's eyes opened wide, but instead of his pupils glowing red, as they normally do when a flash is used, one of his pupils was white.…

A case report describes a novel helmet device that generates a noninvasive oscillating magnetic field and that shrunk a glioblastoma tumor by about a third. This is the first time that the wearable Oncomagnetic device was tried with a patient. The Oncomagnetic device. The patient had end-stage recurrent glioblastoma and…

A practice-changing study that used molecular testing to distinguish between subtypes of medulloblastoma has shown a significant improvement in survival for children with high-risk disease who underwent treatment intensification with carboplatin. "Each of the four subgroups of medulloblastoma has a different prognosis, but for this particular subgroup, 20 fewer children…

Device helmet with 3 oncoscillators securely attached. The oncoscillators are connected to a controller box powered by a rechargeable battery. Credit: Houston Methodist Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating…

IMAGE: EGCG maintains neuronal cell cytoskeleton integrity. Methyl glyoxal treatment leads to glycation of actin and microtubules leading to hampered growth of neuritic extensions and microtubule organization. Microtubule stabilization by +TIP... view more  Credit: Correspondence to - Subashchandrabose Chinnathambi - s.chinnathambi@ncl.res.in Oncotarget published "Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network"…

IMAGE: Expression pattern of ligands of corresponding receptors specific for CD4+ T cell lineages in GBM tumor tissue. (A-D) The heatmaps show expression of the ligands in tumor tissue and graphical... view more  Credit: Correspondence to - Mahua Dey - dey@neurosurgery.wisc.edu Oncotarget published "Genome wide DNA methylation landscape reveals glioblastoma's influence…

A 38-year-old Haitian woman presents to a Florida emergency department in April 2018 reporting pain on the right side of her abdomen, where she can feel a large lump. She tells clinicians she has had significant swelling in her abdomen, despite experiencing weight loss. After palpation of her abdomen confirms…

Part of Dennis Plenker’s daily job is growing cancer. And a variety of different ones, too. Depending on the day and the project, different tumors may burgeon in the petri dishes stocked in the Cold Spring Harbor Laboratory where Plenker works as a research investigator. They might be aggressive breast…

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine. Radiation therapy to the whole brain and spine followed by an extra radiation dose to the back of the brain prevents this spread and…