Blastoma

A practice-changing study that used molecular testing to distinguish between subtypes of medulloblastoma has shown a significant improvement in survival for children with high-risk disease who underwent treatment intensification with carboplatin. "Each of the four subgroups of medulloblastoma has a different prognosis, but for this particular subgroup, 20 fewer children…

Device helmet with 3 oncoscillators securely attached. The oncoscillators are connected to a controller box powered by a rechargeable battery. Credit: Houston Methodist Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating…

IMAGE: EGCG maintains neuronal cell cytoskeleton integrity. Methyl glyoxal treatment leads to glycation of actin and microtubules leading to hampered growth of neuritic extensions and microtubule organization. Microtubule stabilization by +TIP... view more  Credit: Correspondence to - Subashchandrabose Chinnathambi - s.chinnathambi@ncl.res.in Oncotarget published "Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network"…

IMAGE: Expression pattern of ligands of corresponding receptors specific for CD4+ T cell lineages in GBM tumor tissue. (A-D) The heatmaps show expression of the ligands in tumor tissue and graphical... view more  Credit: Correspondence to - Mahua Dey - dey@neurosurgery.wisc.edu Oncotarget published "Genome wide DNA methylation landscape reveals glioblastoma's influence…

A 38-year-old Haitian woman presents to a Florida emergency department in April 2018 reporting pain on the right side of her abdomen, where she can feel a large lump. She tells clinicians she has had significant swelling in her abdomen, despite experiencing weight loss. After palpation of her abdomen confirms…

Part of Dennis Plenker’s daily job is growing cancer. And a variety of different ones, too. Depending on the day and the project, different tumors may burgeon in the petri dishes stocked in the Cold Spring Harbor Laboratory where Plenker works as a research investigator. They might be aggressive breast…

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine. Radiation therapy to the whole brain and spine followed by an extra radiation dose to the back of the brain prevents this spread and…

South of the River, a small fashion boutique based in Beckenham, Kent, is supporting Neuroblastoma UK, a national children’s cancer charity this summer with a limited edition ‘Warrior’ Tile Bracelet. Inspired by children with cancer and designed in collaboration with Neuroblastoma UK, each bracelet features white ‘Warrior’ tiles on a…

IMAGE: Effects of PL on cell cycle-regulatory factors in WERI-Rb and Y79 cells. (A) The expression of CDC25C, CDK1, CCNA2, CCNB1, CDKN1A and CDKN1B was measured at mRNA levels using real... view more  Credit: Correspondence to - Nathalie Allaman-Pillet - nathalie.allaman@gmail.com Oncotarget published "Piperlongumine promotes death of retinoblastoma cancer cells" which…

Home Press release May 07, 2021 11:08 JST Source: Eisai Eisai and Merck & Co., Inc., Kenilworth, N.J., U.S.A. Receive Priority Review From FDA for LENVIMA (lenvatinib) Plus KEYTRUDA (pembrolizumab) Applications For Advanced Renal Cell Carcinoma and for Advanced Endometrial CarcinomaApplications Based on Progression-Free Survival, Overall Survival, and Objective Response…