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Blastoma

“Rogue” DNA Rings Expose Brain Cancer’s Earliest Secrets Blastoma

“Rogue” DNA Rings Expose Brain Cancer’s Earliest Secrets

Scientists report that rogue rings of extrachromosomal DNA (ecDNA) can emerge strikingly early in glioblastoma and may set the tempo for the cancer’s rapid growth and treatment resistance. Often carrying EGFR and quickly evolving, these rings hint at a narrow window for earlier detection and ecDNA-informed intervention. The work elevates…
bubmag
September 13, 2025
Restoring mitochondrial quantity and quality to reverse the Warburg effect and drive neuroblastoma differentiation Blastoma

Restoring mitochondrial quantity and quality to reverse the Warburg effect and drive neuroblastoma differentiation

Proceedings of the National Academy of Sciences, Volume 122, Issue 36, September 2025. SignificanceMitochondrial dysfunction is a hallmark of cancer, driving dedifferentiation and progression. Here, we introduce a mitochondria-centric differentiation therapy that combines retinoic acid (RA) with a mitochondrial uncoupler to restore ...Read More
bubmag
September 5, 2025
Genetic Marker May Guide Brain Cancer Treatment | Mirage News Blastoma

Genetic Marker May Guide Brain Cancer Treatment | Mirage News

University of Kentucky University of Kentucky Markey Cancer Center researchers have discovered a genetic biomarker that could help identify patients with glioblastoma most likely to benefit from the cancer drug bevacizumab. The study, published in JCO Precision Oncology, found that brain tumors from patients treated with bevacizumab who lived longer…
bubmag
July 25, 2025
Baby loses eye to cancer Blastoma

Baby loses eye to cancer

Despite watching her now two-year-old son lose an eye to cancer and facing mounting medical bills, Natalee Whyte-Wilson is clinging to hope and begging other parents not to miss what she didn't know to look for. "Mi want people fi know bout retinoblastoma because mi never know. Mi want other…
bubmag
July 15, 2025
Shocking brain cancer breakthrough: Electric fields supercharge immune assault Blastoma

Shocking brain cancer breakthrough: Electric fields supercharge immune assault

A new study led by Keck Medicine of USC researchers may have uncovered an effective combination therapy for glioblastoma, a brain tumor diagnosis with few available effective treatments. According to the National Brain Tumor Society, the average survival for patients diagnosed with glioblastoma is eight months. The study finds that…
bubmag
June 9, 2025
Brain Cancer Canada Awards $85K to Cutting-Edge Recurrent Glioblastoma Research Blastoma

Brain Cancer Canada Awards $85K to Cutting-Edge Recurrent Glioblastoma Research

TORONTO, May 26, 2025 (GLOBE NEWSWIRE) -- Brain Cancer Canada is pleased to announce a $85,000 research grant awarded to Dr. Stéphane Angers at the University of Toronto for his project, "Discovery of Druggable Vulnerabilities in Hypermutant Recurrent Glioblastoma." This innovative research initiative aims to identify new therapeutic strategies for…
bubmag
May 26, 2025
Brain Cancer Canada Awards $85K to Cutting-Edge Recurrent Glioblastoma Research Blastoma

Brain Cancer Canada Awards $85K to Cutting-Edge Recurrent Glioblastoma Research

Article content TORONTO, May 26, 2025 (GLOBE NEWSWIRE) — Brain Cancer Canada is pleased to announce a $85,000 research grant awarded to Dr. Stéphane Angers at the University of Toronto for his project, “Discovery of Druggable Vulnerabilities in Hypermutant Recurrent Glioblastoma.” This innovative research initiative aims to identify new therapeutic…
bubmag
May 26, 2025
‘Today’ Host Sheinelle Jones’ Husband Uche Ojeh Dead at Age 45 Blastoma

‘Today’ Host Sheinelle Jones’ Husband Uche Ojeh Dead at Age 45

 Today cohost Sheinelle Jones’ husband, Uche Ojeh, has died. “With profound sadness, we share this morning that Uche Ojeh, the husband of our dear friend and Today cohost Sheinelle Jones has passed away after a courageous battle with an aggressive form of brain cancer called glioblastoma,” Savannah Guthrie announced on the…
bubmag
May 23, 2025