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Blastoma

NHS glioblastoma warning signs to watch for after tragic death of author Sophie Kinsella dies at 55 Blastoma

NHS glioblastoma warning signs to watch for after tragic death of author Sophie Kinsella dies at 55

OK Icon Lifestyle Cancer Sophie Kinsella has died at the age of 55 after a battle with glioblastoma, a form of aggressive brain cancer that has a number of concerning symptoms Emilia Randall GAU Writer 16:26, 10 Dec 2025 Best-selling author Sophie Kinsella has tragically died at just 55 following…
bubmag
December 10, 2025
Engineered Virus Enhances Immune Fight Against Glioblastoma | Mirage News Blastoma

Engineered Virus Enhances Immune Fight Against Glioblastoma | Mirage News

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and myeloid cell responses in the tumor microenvironment and increased the overall survival in preclinical models. Results…
bubmag
December 4, 2025
New Tech Promises Precision in Pediatric Brain Tumor Care | Mirage News Blastoma

New Tech Promises Precision in Pediatric Brain Tumor Care | Mirage News

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available. Researchers at Uppsala University have identified a new genetic technique that enables targeting of tumour cells with elevated levels of such proteins. The technique could be…
bubmag
November 10, 2025
“Rogue” DNA Rings Expose Brain Cancer’s Earliest Secrets Blastoma

“Rogue” DNA Rings Expose Brain Cancer’s Earliest Secrets

Scientists report that rogue rings of extrachromosomal DNA (ecDNA) can emerge strikingly early in glioblastoma and may set the tempo for the cancer’s rapid growth and treatment resistance. Often carrying EGFR and quickly evolving, these rings hint at a narrow window for earlier detection and ecDNA-informed intervention. The work elevates…
bubmag
September 13, 2025
Restoring mitochondrial quantity and quality to reverse the Warburg effect and drive neuroblastoma differentiation Blastoma

Restoring mitochondrial quantity and quality to reverse the Warburg effect and drive neuroblastoma differentiation

Proceedings of the National Academy of Sciences, Volume 122, Issue 36, September 2025. SignificanceMitochondrial dysfunction is a hallmark of cancer, driving dedifferentiation and progression. Here, we introduce a mitochondria-centric differentiation therapy that combines retinoic acid (RA) with a mitochondrial uncoupler to restore ...Read More
bubmag
September 5, 2025
Genetic Marker May Guide Brain Cancer Treatment | Mirage News Blastoma

Genetic Marker May Guide Brain Cancer Treatment | Mirage News

University of Kentucky University of Kentucky Markey Cancer Center researchers have discovered a genetic biomarker that could help identify patients with glioblastoma most likely to benefit from the cancer drug bevacizumab. The study, published in JCO Precision Oncology, found that brain tumors from patients treated with bevacizumab who lived longer…
bubmag
July 25, 2025