TFPI2 promotes NK cell–mediated glioblastoma killing through adhesion and checkpoint control
Proceedings of the National Academy of Sciences, Volume 123, Issue 25, June 2026. SignificanceICAM-1/LFA-1 interactions enhance immune cell avidity, stabilizing immune synapses and improving cytotoxicity in solid tumors. The IFNγ signaling pathway was found to be essential for ICAM1 upregulation. Here, we revealed in glioblastoma that ...Read More
bubmagJune 18, 2026