Blastoma

FORMER Utah congresswoman Mia Love has sadly passed away after battling glioblastoma brain cancer.  She leaves behind her husband, Jason, and their three children. Here’s what we know about him. Republican U.S. Rep. Mia Love passed away, surrounded by her family Credit: AP Who is Mia Love’s husband, Jason? Ludmya…

Glioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0 Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy. But new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, suggests a way forward: suppressing a protein called…

A drug developed at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has been shown to extend survival for patients with glioblastoma, the most common primary brain tumor in adults. Results of a trial led by the university revealed that a unique investigational drug…

If you want to make this country great, imagine the strength of a nation whose children have been fought for and know they have been fought for. Last month, my son reached two years in remission from a rare, malignant cancer that almost took his eye and his life. He…

(L to R) Co-first and co-corresponding author Min Pan, Ph.D., co-first author Yinwen Zhang, Ph.D., St. Jude Department of Computational Biology, co-corresponding author John Easton, Ph.D., St. Jude Computational Biology Genomics Laboratory director and senior co-corresponding author Paul Geeleher, Ph.D., St. Jude Department of Computational Biology. Credit: St. Jude Children's…

Proceedings of the National Academy of Sciences, Volume 122, Issue 9, March 2025. SignificanceThe distinctive nature of glioblastoma (GBM) and the blood–brain barrier (BBB) are obstacles for therapies that aim to permanently stop glioma cells from dividing. Similar to reprogramming normal cells, “differentiation therapies” try to push ...Read More

Oncology/Hematology > Other Cancers — Represents the longest reported survival after CAR-T for an active malignancy by Mike Bassett, Staff Writer, MedPage Today February 19, 2025 A neuroblastoma patient treated with CAR T-cell therapy as a child achieved a complete response and remains in remission more than 18 years later.…

A microscopic image of a neuroblastoma tumour Simon Belcher/Alamy A cancer therapy that uses genetically engineered immune cells, called CAR T-cells, has kept a person free of a potentially fatal nerve tumour for a record-breaking 18 years. “This is, to my knowledge, the longest-lasting complete remission in a patient who…

“The first thing that went through my mind was this must be a mistake. It didn’t seem real.” Those were Michael Strahan’s words after he found out that his daughter, Isabella Strahan, had medulloblastoma—a malignant brain tumor. After undergoing a number of surgeries and multiple rounds of chemo and radiation therapy,…

The role of glioma-associated myeloid cells in tumor growth and immune evasion remains poorly understood. We performed single-cell RNA sequencing of immune and tumor cells from 33 gliomas, identifying two distinct myeloid-derived suppressor cell (MDSC) ...Read More