Antibiotics

Researchers from the University of Tübingen and the University of Würzburg have found that ingredients of our daily diet — including caffeine — can influence the resistance of bacteria to antibiotics; they’ve discovered that bacteria such as Escherichia coli orchestrate complex regulatory cascades to react to chemical stimuli from their…

A renowned Nigerian microbiologist, Professor Ali Ajibola Akanbi II of the University of Ilorin, has issued a dire warning over the unchecked misuse of antibiotics, describing it as a growing threat that could trigger a global health crisis worse than any previous pandemic. Speaking during the 288th Inaugural Lecture of…

Escherichia coli is commonly found in the healthy human gut but can also cause infectious disease. A new study finds that certain molecules may push the bug to become more resistant to antibiotics. (Image credit: CAVALLINI JAMES/BSIP/Universal Images Group via Getty Images) Caffeine may help some bacteria keep antibiotics out…

A large analysis of U.S. urgent care visits from 2018 to 2022 found high rates of inappropriate prescribing for antibiotics, glucocorticoids, and opioids. Visits related to COVID were associated with a lower share of antibiotic prescription fills but a higher share of glucocorticoid fills. "Stewardship programs are needed to reduce…

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Proceedings of the National Academy of Sciences, Volume 122, Issue 29, July 2025. SignificanceAcetylation is a modification of protein N termini, lysine residues, antibiotics, and lipids. Many of the enzymes that promote acetylation belong to the GCN5-related N-acetyltransferase (GNAT) family of proteins.Mycobacterium marinumis a ...Read More

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To identify new antimicrobial candidates, scientists at the University of Pennsylvania mined global venomics datasets using a deep-learning system called APEX. Guan et al. demonstrate that venoms are a rich source of previously hidden antimicrobial scaffolds, and that integrating large-scale computational mining with experimental validation can accelerate the discovery of…

Earlier research raised concerns about antibiotic use during the first trimester of pregnancy and risk for congenital malformations. In this study, the risk of malformation was higher for infants exposed to TMP-SMX versus β-lactam antibiotics. Findings support ACOG's recommendation to avoid TMP-SMX during the first trimester but not ACOG's caution…