Category

Antibiotics

Antibiotics

Wildfire smoke may cause life-long harm

Image copyright AFP Image caption Fierce fires have burned thousands of acres of California Smoke from wildfires may have long-term health effects, according to US research on juvenile monkeys.An analysis shows that their immune systems were lower than normal, 12 years after they were naturally exposed to wildfire smoke.There are…
bubmag
February 14, 2020
Antibiotics

How often should you take probiotics? What researchers know so far

There's no daily recommended dose of probiotics because researchers are still studying which strains of probiotics help and how much you need.Many over-the-counter probiotic products contain a range of 1 to 10 billion colony forming units (CFUs).The World Health Organization says some products are effective at levels below 1 billion…
bubmag
February 13, 2020
Antibiotics

Antibiotics discovered that kill bacteria in a new way

A new group of antibiotics with a unique approach to attacking bacteria has been discovered, making it a promising clinical candidate in the fight against antimicrobial resistance. The newly-found corbomycin and the lesser-known complestatin have a never-before-seen way to kill bacteria, which is achieved by blocking the function of the…
bubmag
February 12, 2020
Antibiotics

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling

AbstractAddressing the ongoing antibiotic crisis requires the discovery of compounds with novel mechanisms of action that are capable of treating drug-resistant infections1. Many antibiotics are sourced from specialized metabolites produced by bacteria, particularly those of the Actinomycetes family2. Although actinomycete extracts have traditionally been screened using activity-based platforms, this approach…
bubmag
February 12, 2020
Antibiotics

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling

AbstractAddressing the ongoing antibiotic crisis requires the discovery of compounds with novel mechanisms of action that are capable of treating drug-resistant infections1. Many antibiotics are sourced from specialized metabolites produced by bacteria, particularly those of the Actinomycetes family2. Although actinomycete extracts have traditionally been screened using activity-based platforms, this approach…
bubmag
February 12, 2020
Antibiotics

Draining the swamp

From Jason Crawford, Emergent Ventures winner in Progress Studies: …the surprising thing I found is that infectious disease mortality rates have been declining steadily since long before vaccines or antibiotics… In 1900, the most deaths came from tuberculosis, influenza/pneumonia, and gastroenteric diseases such as dysentery. All of these were effectively conquered…
bubmag
January 29, 2020