Antibiotics

NATURE BRIEFING 20 May 2020 Studies have shown tentatively positive results, but it’s still too soon to say whether the vaccines actually work. Plus: a major update for carbon dating, and the search for a ninth planet in our Solar System. Hello Nature readers, would you like to get this…

In the last few weeks, I’ve lost two patients of mine at the primary care clinic in Charlestown, Massachusetts, where I work as a physician. But I didn’t lose them to COVID-19. I lost them to drugs.  James had been in remission for months from substance use disorder and was…

Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The strong link between glucose control and COVID-19 outcomes has been re-affirmed in the largest study thus far of hospitalized patients with pre-existing type 2 diabetes. The retrospective, multicenter study, from 7337 hospitalized patients with COVID-19,…

Need to Know Published: May 15, 2020 at 8:36 a.m. ET People wear masks as they wait for a bus in Los Angeles on May 14, 2020. Leaving home in Los Angeles now requires bringing a face covering. Associated Press Traders can’t seem to make up their mind this week.…

Multi‐drug resistant (MDR) bacterial pathogens, especially the “ESKAPE” family or the so‐called superbugs, are responsible for ca. two‐thirds of serious infection issues in clinic worldwide.1 Possible solutions involve improvement of antibiotic stewardship as well as new antibiotics.2, 3 As a response to the latter, the European Union supported a series…

Multi‐drug resistant (MDR) bacterial pathogens, especially the “ESKAPE” family or the so‐called superbugs, are responsible for ca. two‐thirds of serious infection issues in clinic worldwide.1 Possible solutions involve improvement of antibiotic stewardship as well as new antibiotics.2, 3 As a response to the latter, the European Union supported a series…

We are four months into a global virus outbreak, and public health awareness could well be at an all-time high. Which is why it is astonishing to discover that 92% of Australians don’t know the difference between a viral infection and a bacterial one.The statistic comes from a survey carried…

For something that has evolved with us over millions of years, and remains part of our physiology over our entire lives, our gut microbiome, oddly, remains somewhat of a mystery. Comprised of trillions of microbes of at least a thousand different species, this community of bacteria, viruses, protozoa and fungi…

Numerous criticisms of medical science have been articulated in recent years. Some critics argue that spurious disease categories are being invented, and existing disease categories expanded, for the aim of profit. Others say that the benefits of most new drugs are minimal and typically exaggerated by clinical research, and that…

AbstractA hexanucleotide-repeat expansion in C9ORF72 is the most common genetic variant that contributes to amyotrophic lateral sclerosis and frontotemporal dementia1,2. The C9ORF72 mutation acts through gain- and loss-of-function mechanisms to induce pathways that are implicated in neural degeneration3,4,5,6,7,8,9. The expansion is transcribed into a long repetitive RNA, which negatively sequesters…