Antibiotics

An efficient divergent synthetic strategy that leverages the natural product spectinomycin to access uniquely functionalized monosaccharides is described. Stereoselective 2′- and 3′-reduction of key spectinomycin-derived intermediates enabled facile access to all eight possible 2,3-stereoisomers of 4,6-dideoxyhexoses as well as representative 3,4,6-trideoxysugars and 3,4,6-trideoxy-3-aminohexoses. In addition, the method was applied to…

The next time you’re gasping for breath in the middle of a cardio routine, try to imagine doing the same thing while decked out in a flowy dress and corset. That’s what female exercise enthusiasts faced in the 1800s. According to Atlas Obscura, tailors weren’t churning out loose leggings or…

While tracing the movement of Escherichia coli, a team of French researchers noticed that near solid surfaces, the bacteria run in circles. Loop after loop, the tracing almost looks like an Olympic figure skating rink before the Zamboni irons the sheet of ice smooth. Breaking down E. coli's routine step…

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AbstractMicrobial biofilm formation on indwelling medical devices causes persistent infections that cannot be cured with conventional antibiotics. To address this unmet challenge, we engineer tunable active surface topographies with micron-sized pillars that can beat at a programmable frequency and force level in an electromagnetic field. Compared to the flat and static…

Are you Ready for Insta 75 Days Revision Plan (UPSC Prelims - 2020)?  Introduction: All of us know what antibiotics are, in fact, whenever we suffer a severe infection, our medical practitioner prescribes these powerful medicines to help us fight the infection caused by bacteria. Also known as antimicrobial…

Overuse of antibiotics, high animal numbers and low genetic diversity caused by intensive farming techniques increase the likelihood of pathogens becoming a major public health risk, according to new research led by UK scientists. An international team of researchers led by the Universities of Bath and Sheffield, investigated the evolution…

By fmyactuallife - 3/5/2020 08:00 Today, I'm on my second day of a week of antibiotics to treat a bad urine infection. Incidentally, the pills seem to be giving me extremely loud, frequent, gut-wrenchingly painful and smelly diarrhea. Only 5 more days to go. FML By Jenievonteese - 12/6/2011 23:33…

Scientists exploiting a ‘chink’ in cell’s armor plating Scientists have identified a key process in the way bacteria protect themselves from attack – and it heralds a new strategy in the hunt for antibiotics.The researchers from the University of Leeds have pieced together how bacteria build their outer, defensive wall…

Photo: Bruce Bennett/Getty Images.The Centers for Disease Control and Prevention currently lists about 13 symptoms that they say are related to coronavirus on their website. Six of those COVID-19 symptoms were added recently. But one possible red flag we've been hearing a lot about lately is missing from the catalog:…