Antibiotics

TOPLINE: Antibiotic use does not appear to be associated with microscopic colitis (MC), despite presenting with similar symptoms of watery, non-bloody diarrhea.  METHODOLOGY: MC, a change in the microbiome characterized by watery, non-bloody diarrhea, can significantly worsen a patient’s quality of life; antibiotic treatment may induce similar symptoms, but the…

Physicians have seriously warned against the use of antibiotics by pregnant women without a doctor’s prescription, highlighting the potential risks, particularly during the first trimester. The medics in the field of obstetrics and gynaecology said women should always remember that not all medicines are safe to use during pregnancy including…

 The misuse and overuse of antibiotics has been identified as a contributing factor to the growing challenge of Antimicrobial Resistance (AMR).  Dr. Columba Teri Vakuru, Nigeria’s Chief Veterinary Officer raised the alarm over the global threat of AMR, at the two-day awareness and sensitization workshop held in Awka, Anambra State. …

Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025. SignificanceMycobacterial infections are among the leading causes of human deaths globally. Ribosome-targeting antibiotics are often included among their treatment regimens. HflX is a bacterial stress-response protein that binds to the 70S ribosomes and ...Read More

Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025. SignificanceBacterial cytological profiling (BCP) is a well-established method to determine the mechanism of action (MOA) for antibiotics by examining the morphological changes that occur when bacteria are treated with a compound of interest...Read More

The conventional wisdom on why some antibiotics don’t work rests on the concept of persistence. A small subset of bacteria sometimes hides out and escapes the effects of the drugs meant to kill them. These persisters can then come back with a vengeance and may no longer respond to the…

Oysters have long been considered an aphrodisiac. Now, the mollusk might be tapped to fight infectious diseases. A study shows that proteins in the blood, or hemolymph, of a Sydney Rock Oyster not only kills bacteria but boosts some antibiotics’ efficacies against several resistant strains, according to a study in…

In their battle against antibiotics, bacteria are gaining an edge, becoming more and more resistant to antibiotic attacks. But a new paper published in PLOS Biology suggests that computer models could contribute to making more targeted antibiotics, with a reduced risk of increasing bacteria’s antibiotic resistance. According to the authors…

A groundbreaking study has unveiled how Staphylococcus aureus, a bacterium often found in humans, evolves and survives, offering promising leads for better infection management. By analyzing thousands of bacterial samples directly from humans rather than in lab settings, researchers identified crucial genetic mutations that help these bacteria resist antibiotics and…

“I found several culture plates where none of the six antibiotics placed on them had any effect on the bacteria,” recalled Habibullah Ibuowo, a 400-level Medical Laboratory Science student. His startling discovery occurred during a 10-week clinical training required for Medical Laboratory Science (MLS) students. It was his first encounter…