Antibiotics

TOPLINE: In a large cohort, long-acting lipoglycopeptides (laLGPs) demonstrated comparable effectiveness to standard-of-care antibiotics for step-down treatment of serious Gram-positive bacterial infections in both individuals who used drugs and those who did not. METHODOLOGY: Standard antibiotic therapy for serious bacterial infections can be challenging due to stigma and logistical barriers…

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The UTI-Diag project, a groundbreaking multisectoral initiative, officially launches with key objectives to: (i) improve the detection and management of urinary tract infections (UTIs); (ii) reduce the inappropriate use of antibiotics and help fight antibiotic resistances (AMR) in human health; and (iii) enhance access, adoption, and implementation of novel diagnostic…

Nearly a third of all antibiotics that people consume end up in the world’s rivers, a new study finds. This could potentially harm aquatic life and impact human health by promoting drug resistance, researchers say. Antibiotics, critical for treating various bacterial infections, are widely consumed by people...Read More

A new screening method to tackle bacterial resistance in a type of antibiotics has been developed by researchers at the University of Oxford. Scientists from the Ineos Oxford Institute for Antimicrobial Research have created the method to combat resistance to tetracycline antibiotics. The results provide a foundation for developing new…

Millions of kilometres of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a McGill University-led study warns. Published in PNAS Nexus, the study is the first to estimate the scale of global river contamination from human antibiotics use.…

One of the most commonly taken drugs in the UK can trigger a debilitating cough that takes up to three months to disappear, a GP has warned. Ace inhibitors, used to treat high blood pressure, account for around 65million prescriptions in the UK every year.  The drugs, which include Ramipril, Lisinopril…

Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025. SignificanceA major medical challenge is the spread of bacteria which are resistant to antibiotics. The resistance genes are spread via mobilized DNA, mainly via a process named conjugation. During conjugation, a resistant bacterium (donor...Read More

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