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Amyloid precursor protein and C99 are subunits in human microglial Hv1 channels that enhance current and inflammatory mediator release Cursor

Amyloid precursor protein and C99 are subunits in human microglial Hv1 channels that enhance current and inflammatory mediator release

Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. SignificanceMicroglial-mediated neuroinflammation is strongly implicated in the development and progression of Alzheimer’s disease (AD). Here we demonstrate that human induced pluripotent stem cell (iPSC)-microglia (iMG) employ voltage-gated proton ...Read More
bubmag
October 23, 2025
Cursor, Windsurf IDEs riddled with 94+ n-day Chromium vulnerabilities Cursor

Cursor, Windsurf IDEs riddled with 94+ n-day Chromium vulnerabilities

The latest releases of Cursor and Windsurf integrated development environments are vulnerable to more than 94 known and patched security issues in the Chromium browser and the V8 JavaScript engine. An estimated 1.8 million developers, the userbase for the two IDEs, are exposed to the risks. Ox Security researchers explain that both development environments…
bubmag
October 21, 2025
Exclusive: David Tisch’s BoxGroup raises $550 million across two new funds as venture firm crosses 16 years Cursor

Exclusive: David Tisch’s BoxGroup raises $550 million across two new funds as venture firm crosses 16 years

Venture capital performance may be measured in ten-year chunks, but only an elite club of firms can claim to have stayed consistent—let alone functional—for anywhere close to that timeframe. David Tisch’s BoxGroup, which boasts 16 years of operation and just closed $550 million in new funding, can claim a spot…
bubmag
October 21, 2025
230-Million-Year-Old Headless Fossil in Argentina Is One of the World’s Oldest Dinosaurs Cursor

230-Million-Year-Old Headless Fossil in Argentina Is One of the World’s Oldest Dinosaurs

One of the world’s oldest dinosaurs has been discovered in Argentina — it just happens to be missing its head. Scientists working in La Rioja discovered the 230-million-year-old fossil in the foothills of a mountain range. The study, published in Nature , introduces us to a new long-necked species, named…
bubmag
October 20, 2025