A conserved E3 ubiquitin ligase rewires carotenoid, sterol, and lipid metabolism in Xanthophyllomyces dendrorhous
Proceedings of the National Academy of Sciences, Volume 123, Issue 17, April 2026. SignificanceEukaryotic cells must balance the biosynthesis of sterols, lipids, and in many organisms, carotenoids, which draw on shared acetyl-CoA-derived precursors. Our study identifies the ubiquitin ligase PTR1 as a regulator that coordinates these ...Read More
bubmagApril 24, 2026