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Proceedings of the National Academy of Sciences, Volume 122, Issue 49, December 2025. SignificanceBiotin is an essential enzyme cofactor, and inhibitors of its biosynthesis could provide alternative antibiotics. We show that bacteria from the Weeksellaceae family access the universal biotin precursor, pimelic acid, by a distinct pathway ...Read More

Proceedings of the National Academy of Sciences, Volume 122, Issue 49, December 2025. SignificancePreneoplastic cells often appear histologically normal yet carry early genetic and transcriptional changes, leading to malignant transformation. In this study, we combine genetic barcoding with single-cell transcriptomics to uncover the ...Read More

- Monday, December 01, 2025 Christopher Musa, the immediate past chief of defence staff (CDS), met with President Bola Tinubu at the State House in Abuja on Monday. It is understood that the meeting is a precursor to a major shake-up by Tinubu in the wake of growing insecurity in…

Proceedings of the National Academy of Sciences, Volume 122, Issue 48, December 2025. SignificanceShoot stem cells are precursors of aboveground tissues. A precise regulatory basis is required to control their activity during plant development. This study reveals that APETALA2-like transcription factors in hybrid aspen play a central role ...Read More

PromptVibe is a digital platform designed to enhance productivity for professionals and businesses by providing a suite of AI-driven resources. These resources include custom AI prompts, expert-level coding tips, and tailored Cursor IDE rules, all aimed at streamlining workflows and improving efficiency. Key Features AI-Powered Generator: This tool enables users…

Home » Artificial intelligence » Google Gemini 3 is Here Gemini 3 is here and it edges out XAI Grok 4.1 as the state of the art model topping the leaderboards. This is likely be the best for coding in Apps with tool use. The new agentic development platform, Google…

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Researchers at Tokyo Metropolitan University have turned to concepts from polymer physics to better understand a central feature of Alzheimer's disease: the formation of tau protein fibrils. Their work revealed that these fibrils do not appear suddenly. Instead, they emerge after large clusters of tau proteins begin to gather in…

A newly identified carnivorous reptile may look like a dinosaur at first glance, but researchers have confirmed that it was actually an early relative of modern crocodiles. The species is named Tainrakuasuchus bellator, a title partly inspired by the Latin word for "warrior" or "fighter." This armored animal lived 240…

Democracy Dies in Darkness Thai officials inspect a seized shipment of approximately 10 million methamphetamine tablets most likely manufactured in labs in neighboring Myanmar, officials said. (Photos by Sirachai Arunrugstichai/For The Washington Post) Chinese manufacturers are shipping meth precursor chemicals to warlords in Myanmar, precipitating a drug crisis across the…