Antibiotics

AbstractAddressing the ongoing antibiotic crisis requires the discovery of compounds with novel mechanisms of action that are capable of treating drug-resistant infections1. Many antibiotics are sourced from specialized metabolites produced by bacteria, particularly those of the Actinomycetes family2. Although actinomycete extracts have traditionally been screened using activity-based platforms, this approach…

When it comes to taking probiotics, you have two main options — probiotic supplements or probiotic-containing foods like yogurt and sauerkraut. However, contrary to popular health trends, not everyone needs probiotics on a regular basis. Here's what you need…

Its almost like a creep, very gradually occurring, says University of Alberta pathologist Gregory Tyrell, who was not involved with the study. Whats more, he says, the paper shows that this is not a rare event. Musser and colleagues didnt find samples in thei…

The color-changing, paper-based bandages that the team created start out green. If a material embedded in the bandage detects an acidic environment, typically caused by bacterial infection, it will turn yellow and release an antibiotic that kills non-resistan…

From Jason Crawford, Emergent Ventures winner in Progress Studies: …the surprising thing I found is that infectious disease mortality rates have been declining steadily since long before vaccines or antibiotics… In 1900, the most deaths came from tuberculosis, influenza/pneumonia, and gastroenteric diseases such as dysentery. All of these were effectively conquered…

The FDA sent a warning letter to Gojo Industries, Purell's parent company, telling the company to stop claiming that its hand sanitizer can prevent diseases like Ebola and MRSA.Gojo said it will remove the misleading language from its website. Some of the claims the FDA objected to appear to have…

The world is in the midst of a global superbug crisis. Antibiotic resistance has been found in numerous common bacterial infections, including tuberculosis, gonorrhea, and salmonellosis, making them difficult if not impossible to treat. Were on the cusp of a …

A 52-year-old hairdresser developed a life-threatening blood disorder her doctors believe was the result of "Brazilian blowdry" treatments she'd been preparing for clients. The case, published in the January issue of BMJ Case Reports, is the first of its kin…

The FDA has given clearance for the first clinical trial in the United States to test an IV-administered bacteriophage-based therapy to kill drug-resistant bacteria. The agency accepted an investigational new drug application for the planned trial from researchers at the University of California, San Diego, according to a news release.…

Nova Scotia is declaring a provincial outbreak of syphilis after seeing a jump in the number of cases last year. Public health officials said today there were 82 cases recorded in 2019, compared with 50 in 2018 and 38 in 2017. Twenty per cent of the cases l…