Category

Antibiotics

Giving antibiotics an assist Antibiotics

Giving antibiotics an assist

SummaryAntimicrobial resistance (AMR) is the silent pandemic. It has been steadily increasing over many years and threatens to halt the practice of modern medicine. By 2050, the annual number of worldwide deaths due to AMR will be ∼10 million, with an estimated economic impact of 100 trillion USD (1). The…
bubmag
June 10, 2021
Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance Antibiotics

Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance

Turning down tolerancePersister cells, which are found in abundance in biofilms, adopt a quiescent state and survive antimicrobial treatments, seeding disease recurrence and incubating new resistance mutations. Building on work implicating the reactive small-molecule hydrogen sulfide in bacterial defense against antibiotics, Shatalin et al. conducted a structure-based screen for inhibitors…
bubmag
June 10, 2021
New defence against superbugs Antibiotics

New defence against superbugs

IMAGE: Dr Bart Eijkelkamp, left, and researchers Felice Adams and Maoge Zang at the Bacterial Host Adaptation Research Laboratory at Flinders University, South Australia view more  Credit: Flinders University For the first time, Australian scientists have confirmed a link between the role of regular fish oil to break down the ability…
bubmag
June 9, 2021
Surveillance and One Health in food production key to halting antimicrobial resistance Antibiotics

Surveillance and One Health in food production key to halting antimicrobial resistance

Antimicrobial agents, such as antibiotics, are essential to treating many human and animal infections and diseases. Their overuse and misuse, however, has led to the development of antimicrobial resistance (AMR), meaning that a drug, such as an antibiotic, might no longer be effective in treating the infection. Without urgent action,…
bubmag
June 7, 2021
Antibiotics no help for mysterious lung-scarring disease, large trial finds Antibiotics

Antibiotics no help for mysterious lung-scarring disease, large trial finds

IMAGE: Imre Noth, MD, the chief of UVA Health's Division of Pulmonary and Critical Care Medicine, says the large study of idiopathic pulmonary fibrosis will still benefit efforts to battle the... view more  Credit: UVA Health Doctors have hoped that antibiotics could benefit patients with chronic lung diseases, but a new…
bubmag
June 2, 2021
Can antibiotics treat human diseases in addition to bacterial infections? Antibiotics

Can antibiotics treat human diseases in addition to bacterial infections?

According to researchers at the University of Illinois Chicago, the antibiotics used to treat common bacterial infections, like pneumonia and sinusitis, may also be used to treat human diseases, like cancer. Theoretically, at least. As outlined in a new Nature Communications study, the UIC College of Pharmacy team has shown…
bubmag
May 25, 2021
New Bacteria Species Found in Snake Poop Resists 35 Types of Antibiotics, Could Spread to Humans Antibiotics

New Bacteria Species Found in Snake Poop Resists 35 Types of Antibiotics, Could Spread to Humans

Indian researchers say they have isolated two new species of antibiotic-resistant bacteria from the scat, or fecal matter, of a vine snake, a mildly venomous reptile found throughout South and Southeast Asia, according to a March 14 article in the scientific journal Antonie van Leeuwenhoek. The new species are resistant…
bubmag
May 24, 2021