Antibiotics

Pln149-PEP20 time-kill against (a) S. aureus ATCC 25923 (MIC = 8 mg/L) and (b) S. aureus SA43 (MIC = 8 mg/L). Credit: Antibiotics (2023). DOI: 10.3390/antibiotics12020391 Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug…

Why some people recover from Lyme disease, while others experience months, years or even decades of chronic symptoms has long puzzled doctors. New research offers some clues to an immune system marker in the blood that is elevated among people with lingering Lyme disease symptoms, even after they’d received antibiotics. …

Clostridioides difficile (C. difficile) is a bacterium that can infect the large intestine, with symptoms ranging from diarrhea to life-threatening colon damage. A study publishing May 11th in PLOS Biology by Ophelia Venturelli at University of Wisconsin-Madison, USA, and colleagues suggests that between-species interactions within the gut microbiome may impact…

Key PointsNSW Government to roll out trial from Monday to access UTI medication at dozens of pharmacies.Access will be available to women aged between 18 and 65 showing signs of an uncomplicated UTI.Doctor advocacy groups fear the trial could risk patient safety.Women in NSW will soon have easier access to…

Victoria Powers, from Wolverhampton, had bravely fought off breast cancer five years earlier only to eventually be given the heartbreaking news that the disease had returned Mother-of-one Victoria was diagnosed with lung cancer after overcoming breast cancer and her friends are raising money for her and her familyA mother who…

Phage therapy is an exciting alternative to antibiotics. Why now? Our world today is reliant on antibiotics to fight bacterial infections, but the way we use them has created new, drug-resistant ‘superbugs’ that have evolved to be resistant to most antibiotics. These killed at least 1.27 million people worldwide in…

Clostridioides difficile (C. diff) is a type of bacterium that can cause infection in the gut, leading to symptoms such as diarrhea, abdominal pain, and fever. C. diff infections are often a result of an imbalance in the gut microbiome, which can occur after taking antibiotics. According to a recent…

Breast cancer is the most common cancer in women worldwide. The immune system plays a crucial role in determining outcomes. Triple-negative breast cancer (TNBC) is the most lethal subtype, disproportionately affecting ethnic minorities and those with lower socioeconomic status. Despite advances in therapy, TNBC has inferior outcomes compared to non-triple-negative…

Ancient DNA preserved in the tooth tartar of human fossils encodes microbial metabolites that could be the next antibiotic. Credit: Werner/Siemens Foundation Microorganisms—in particular bacteria—are skillful chemists that can produce an impressive diversity of chemical compounds known as natural products. These metabolites provide the microbes major evolutionary advantages, such as…

Bacteria have lived on our planet earth for about 3 billion years, most of the 4.5 billion years that the planet has been around. And while the industrious microbes are central to medicine, disease and most areas of the natural world, we understand little about the form they took in…