Antibiotics

The Nigeria Centre for Disease Control and Prevention ( NCDC) has enjoined pharmacists across the country to increase efforts towards surveillance and rational prescription of antimicrobials. Antimicrobials usually called drugs or medicines are substances used to treat, kill or stop a wide variety of infectious diseases in humans and animals…

Health Bacterial vaginosis, which is caused by bacteria overgrowing in the vagina, can be hard to treat, with women often experiencing recurring symptoms. Now it seems that asking their male sexual partners to use antibiotic pills and cream could be key to tackling the condition By Carissa Wong Facebook /…

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The search for a solution to antimicrobial resistance found something. And researchers found it in a true “it’s always the last place you look” location. Australian oysters. Or more specifically, Australian oyster blood. We know antimicrobial resistance claims at least 1 million lives each year, and experts suspect that number…

TOPLINE: Antibiotic use does not appear to be associated with microscopic colitis (MC), despite presenting with similar symptoms of watery, non-bloody diarrhea.  METHODOLOGY: MC, a change in the microbiome characterized by watery, non-bloody diarrhea, can significantly worsen a patient’s quality of life; antibiotic treatment may induce similar symptoms, but the…

Physicians have seriously warned against the use of antibiotics by pregnant women without a doctor’s prescription, highlighting the potential risks, particularly during the first trimester. The medics in the field of obstetrics and gynaecology said women should always remember that not all medicines are safe to use during pregnancy including…

 The misuse and overuse of antibiotics has been identified as a contributing factor to the growing challenge of Antimicrobial Resistance (AMR).  Dr. Columba Teri Vakuru, Nigeria’s Chief Veterinary Officer raised the alarm over the global threat of AMR, at the two-day awareness and sensitization workshop held in Awka, Anambra State. …

Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025. SignificanceMycobacterial infections are among the leading causes of human deaths globally. Ribosome-targeting antibiotics are often included among their treatment regimens. HflX is a bacterial stress-response protein that binds to the 70S ribosomes and ...Read More

Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025. SignificanceBacterial cytological profiling (BCP) is a well-established method to determine the mechanism of action (MOA) for antibiotics by examining the morphological changes that occur when bacteria are treated with a compound of interest...Read More

The conventional wisdom on why some antibiotics don’t work rests on the concept of persistence. A small subset of bacteria sometimes hides out and escapes the effects of the drugs meant to kill them. These persisters can then come back with a vengeance and may no longer respond to the…