Category

Antibiotics

Centre should increase Budget allocation of health in line with promise of 2.5% of GDP: JSA Antibiotics

Centre should increase Budget allocation of health in line with promise of 2.5% of GDP: JSA

Calling for doubling of allocations to the National Health Mission, JSA said, it should be used for strengthening and expansion of health services, improvement of health and wellness centres, and ensuring justice to health staff, including ASHAs and contractual workers | Photo Credit: Getty Images Civil society group Jan Swasthya…
bubmag
January 28, 2026
Study sheds light on the function of a key antibiotic-producing enzyme Antibiotics

Study sheds light on the function of a key antibiotic-producing enzyme

Researchers have successfully replaced a section of the antibiotic-synthesizing enzyme PikAIII-M5, advancing our understanding of its structure and function and moving us closer to the creation of synthetic antibiotics. Credit: Tohoku University Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely…
bubmag
January 22, 2026
Why Antibiotics Aren’t Enough for Some Chronic Wounds Antibiotics

Why Antibiotics Aren’t Enough for Some Chronic Wounds

Researchers found that a common antibiotic-resistant bacterium prevents wounds from healing by chemically paralyzing skin cells rather than attacking them directly. Scientists from an international research group led by Nanyang Technological University, Singapore (NTU Singapore), have identified an approach that may help chronic wounds heal faster...Read More
bubmag
January 16, 2026
An activator of a two-component system controls cell separation and intrinsic drug resistance in Mycobacterium tuberculosis Antibiotics

An activator of a two-component system controls cell separation and intrinsic drug resistance in Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences, Volume 123, Issue 3, January 2026. SignificanceThe bacterium that causes tuberculosis,Mycobacterium tuberculosis, is inherently resistant to many antibiotics. The mechanisms that mediate this resistance are not yet fully understood. Here, we identify a protein, here named TapA, that is ...Read More
bubmag
January 16, 2026
Redefining Shiga toxin–induced human cell death as NLRP1-mediated pyroptosis Antibiotics

Redefining Shiga toxin–induced human cell death as NLRP1-mediated pyroptosis

Proceedings of the National Academy of Sciences, Volume 123, Issue 3, January 2026. SignificanceTreatment options for life-threatening kidney and intestinal diseases caused by EnterohemorrhagicEscherichia coli(EHEC)—affecting 265,000 people, especially children, per annum in the United States—are limited as antibiotics are ...Read More
bubmag
January 14, 2026
The innate immune protein calprotectin ablates the bactericidal activity of β-lactam antibiotics Antibiotics

The innate immune protein calprotectin ablates the bactericidal activity of β-lactam antibiotics

Proceedings of the National Academy of Sciences, Volume 123, Issue 3, January 2026. SignificanceAntibiotic failure is a major clinical problem that cannot always be explained by traditional resistance mechanisms. This study reveals that the host immune protein calprotectin, which is abundant at infection sites, can interfere with β...Read More
bubmag
January 14, 2026
Metal compounds identified as potential new antibiotics, thanks to robots doing ‘click chemistry’ Antibiotics

Metal compounds identified as potential new antibiotics, thanks to robots doing ‘click chemistry’

Scientists identified a promising antibiotic active ingredient, and it contains the metal iridium (pictured above). (Image credit: RHJ/Getty Images) An iridium metal complex has been identified as a promising, if unconventional, new antibiotic drug, a new study finds. The compound is one of more than 600 produced in a study…
bubmag
January 12, 2026
Visiting abroad in the coming year? Antibiotics becoming less effective against traveler’s diarrhea, study warns Antibiotics

Visiting abroad in the coming year? Antibiotics becoming less effective against traveler’s diarrhea, study warns

Planning some international travel as one of your New Year's resolutions? Then be forewarned: Travelers' diarrhea is becoming harder to treat. The antibiotics typically used to treat travelers' diarrhea are becoming less effective, researchers recently reported in JAMA Network Open. Specifically, the bacteria that cause the illness are showing increased…
bubmag
December 30, 2025