A steady-state pool of calcium-dependent actin is maintained by Homer and controls epithelial mechanosensation
Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. SignificanceThis study uncovers a mechanism by which localized calcium dynamics at the apical junctional complex (AJC) maintain an adaptive, tension sensitive pool of actin, regulated by the epithelial polarity scaffolds Homer and MUPP1/PatJ...Read More
bubmagOctober 24, 2025