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Alexander von Humboldt

Alexander von Humboldt

The Influence of Nanoparticle Shape on Protein Corona Formation

Nanoparticles (NPs) have become an integral part of many aspects of modern medicine, becoming utility in a wide range of areas such as drug delivery, medical imaging, and diagnostics. In this context, mesoporous silica nanoparticles (MSNs) are particularly interesting for medical applications because of their biocompatibility, biodegradability, large surface‐to‐volume ratio,…
bubmag
May 14, 2020
Alexander von Humboldt

The Influence of Nanoparticle Shape on Protein Corona Formation

Nanoparticles (NPs) have become an integral part of many aspects of modern medicine, becoming utility in a wide range of areas such as drug delivery, medical imaging, and diagnostics. In this context, mesoporous silica nanoparticles (MSNs) are particularly interesting for medical applications because of their biocompatibility, biodegradability, large surface‐to‐volume ratio,…
bubmag
May 14, 2020
Alexander von Humboldt

ANGLO 5CONSPIRACY THEORIESHEADLINE NEWSHow Huxley’s X-Club Created Nature Magazine And Sabotaged Science For 150 Years

Amidst the storm of controversy raised by the lab-origin theory of COVID-19 extolled by such figures as Nobel prize winning virologist Luc Montagnier, researcher Judy Mikowits, bioweapons expert Francis Boyle, Sri Lankan Cardinal Malcolm Ranjith and the head of Iran’s Revolutionary Guard, an elaborate project was undertaken under the nominal…
bubmag
May 14, 2020
Alexander von Humboldt

Noble metal aerogels enabled by freezing

As a new class of porous materials, noble metal aerogels (NMAs) have drawn tremendous attention because of their combined features including self-supported architectures, high surface areas, and numerous optically and catalytically active sites, enabling their impressive performance in diverse fields. However, current fabrication methods suffer from long fabrication periods, unavoidable…
bubmag
May 13, 2020
Alexander von Humboldt

The Story of Charles Willson Peale’s Massive Mastodon

SMITHSONIANMAG.COM | May 6, 2020, 10:44 a.m. In the 18th century, French naturalist George-Louis Leclerc, Comte du Buffon (1706-1778), published a multivolume work on natural history, Histoire naturelle, générale et particuliére. This massive treatise, which eventually grew to 44 quarto volumes, became an essential reference work for anyone interested in…
bubmag
May 6, 2020
Alexander von Humboldt

A Pronucleotide Probe for Live‐Cell Imaging of Protein AMPylation

Protein AMPylation is a highly abundant post‐translational modification (PTM)1 regulating unfolded protein response (UPR),2-4 differentiation of neural progenitors and α‐synuclein modification.5, 6 AMPylation is catalyzed by AMP transferases (AMPylators), which transfer adenosine 5′‐O ‐monophosphate from substrate ATP onto Ser, Thr or Tyr residues in target proteins (Scheme 1 A).1, 7 The only…
bubmag
May 6, 2020
Alexander von Humboldt

Selective ortho‐Functionalization of Adamantylarenes Enabled by Dispersion and an Air‐Stable Palladium(I) Dimer

Owing to its exceptional liphophilicity and stability‐enhancing properties, the adamantyl group has found widespread applications in materials science,1 medicinal chemistry, and drug development.2 In fact, the only other hydrocarbon moiety that has been similarly successful in generating active therapeutics is the methyl group.2 Adamantane derivatives are used in fighting viral…
bubmag
May 4, 2020